論文- 内田 康雄 -
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件数:42件
[2019]
1.Amyloid beta(25-35) impairs docosahexaenoic acid efflux by down-regulating fatty acid transport protein 1 (FATP1/SLC27A1) protein expression in human brain capillary endothelial cells.[J Neurochem,150(4),(2019),385-401]Ochiai Y, Uchida Y, Tachikawa M, Couraud PO, Terasaki T
10.1111/jnc.14722
2.Involvement of claudin-11 in disruption of blood-brain, -spinal cord and -arachnoid barriers in multiple sclerosis.[Mol Neurobiol,56(3),(2019),2039-2056]Y Uchida, T Sumiya, M Tachikawa, T Yamakawa, S Murata, Y Yagi, K Sato, A Stephan, K Ito, S Ohtsuki, PO Couraud, T Suzuki, and T Terasaki
10.1007/s12035-018-1207-5
3.Oxidative stress-induced activation of Abl and Src kinases rapidly induces P-glycoprotein internalization via phosphorylation of caveolin-1 on tyrosine-14, decreasing cortisol efflux at the blood-brain barrier.[J Cereb Blood Flow Metab,Accepted for publication,(2019)]Uchida Y (co-first author), Hoshi Y, Tachikawa M, Ohtsuki S, Couraud PO, Suzuki T, Terasaki T
10.1177/0271678X18822801
4.Selective Protein Expression Changes of Leukocyte-Migration-Associated Cluster of Differentiation Antigens at the Blood-Brain Barrier in a Lipopolysaccharide-Induced Systemic Inflammation Mouse Model without Alteration of Transporters.[Biol Pharm Bull,42(6),(2019),944-953]Sato K, Tachikawa M, Watanabe M, Uchida Y, Terasaki T
10.1248/bpb.b18-00939
5.Toward a Consensus on Applying Quantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper.[Clin Pharmacol Ther,106(3),(2019),525-543]Prasad B, Achour B, Artursson P, Hop CECA, Lai Y, Smith PC, Barber J, Wisniewski JR, Spellman D, Uchida Y, Zientek MA, Unadkat JD, Rostami-Hodjegan A
10.1002/cpt.1537
6.Distinct roles of ezrin, radixin and moesin in maintaining the plasma membrane localizations and functions of human blood-brain barrier transporters.[J Cereb Blood Flow Metab,Accepted for publication,(2019)]Hoshi Y, Uchida Y, Kuroda T, Tachikawa M, Couraud PO, Suzuki T, Terasaki T
10.1177/0271678X19868880
7.Abundant expression of OCT2, MATE1, OAT1, OAT3, PEPT2, BCRP, MDR1 and xCT transporters in blood-arachnoid barrier of pig, and polarized localizations at CSF- and blood-facing plasma membranes.[J Neurochem,Accepted for publication,(2019)]Yasuo Uchida, Ryohei Goto, Hina Takeuchi, Magdalena Łuczak, Takuya Usui, Masanori Tachikawa and Tetsuya Terasaki
[2018]
8.High Expression of UGT1A1/1A6 in Monkey Small Intestine: Comparison of Protein Expression Levels of Cytochromes P450, UDP-Glucuronosyltransferases, and Transporters in Small Intestine of Cynomolgus Monkey and Human.[Mol Pharm.,15(1),(2018),127-140]Akazawa T, Uchida Y, Miyauchi E, Tachikawa M, Ohtsuki S, Terasaki T
10.1021/acs.molpharmaceut.7b00772
9.ATP-binding cassette transporter A subfamily 8 is a sinusoidal efflux transporter for cholesterol and taurocholate in mouse and human liver.[Mol Pharm.,15(2),(2018),343-355]Sasaki K, Tachikawa M, Uchida Y, Hirano S, Kadowaki F, Watanabe M, Ohtsuki S, Terasaki T
10.1021/acs.molpharmaceut.7b00679
10.Drug clearance from cerebrospinal fluid mediated by organic anion transporters 1 (Slc22a6) and 3 (Slc22a8) at arachnoid membrane of rats.[Mol Pharm.,15(3),(2018),911-922]Zhang Z, Tachikawa M, Uchida Y, Terasaki T
10.1021/acs.molpharmaceut.7b00852
[2017]
11.Actin filament-associated protein 1 (AFAP-1) is a key mediator in inflammatory signaling-induced rapid attenuation of intrinsic P-gp function in human brain capillary endothelial cells.[J Neurochem.,141(2),(2017),247-262]Uchida Y (co-first author), Hoshi Y, Tachikawa M, Ohtsuki S, Terasaki T
10.1111/jnc.13960
12.Inner blood-retinal barrier dominantly expresses breast cancer resistance protein: Comparative quantitative targeted absolute proteomics (QTAP) study of CNS barriers in pig.[Mol Pharm.,14(11),(2017),3729-3738]Zhang Z, Uchida Y, Hirano S, Ando D, Kubo Y, Auriola S, Akanuma S, Hosoya K, Urtti A, Terasaki T, Tachikawa M
10.1021/acs.molpharmaceut.7b00493
13.The blood-brain barrier fatty acid transport protein 1 (FATP1/SLC27A1) supplies docosahexaenoic acid to the brain, and insulin facilitates transport.[J Neurochem.,141(3),(2017),400-412]Ochiai Y, Uchida Y, Ohtsuki S, Tachikawa M, Aizawa S, Terasaki T
10.1111/jnc.13943
[2016]
14.Quantitative Targeted Absolute Proteomics of Transporters and Pharmacoproteomics-Based Reconstruction of P-Glycoprotein Function in Mouse Small Intestine.[Mol Pharm.,13(7),(2016),2443-2456]Akazawa T, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T
10.1021/acs.molpharmaceut.6b00196
15.Quantitative targeted absolute proteomics for 28 transporters in brush-border and basolateral membrane fractions of rat kidney.[J Pharm Sci.,105,(2016),1011-1016]Uchida Y, Toyohara T, Ohtsuki S, Moriyama Y, Abe T and Terasaki T
10.1002/jps.24645
[2015]
16.Major involvement of Na(+) -dependent multivitamin transporter (SLC5A6/SMVT) in uptake of biotin and pantothenic acid by human brain capillary endothelial cells..[J Neurochem,134(1),(2015),97-112]Uchida Y, Ito K, Ohtsuki S, Kubo Y, Suzuki T and Terasaki T
10.1111/jnc.13092
http://www.ncbi.nlm.nih.gov/pubmed/25809983
17.Genomic Knockout of Endogenous Canine P-Glycoprotein in Wild-Type, Human P-Glycoprotein and Human BCRP Transfected MDCKII Cell Lines by Zinc Finger Nucleases..[Pharm Res,32(6),(2015),2060-2071]Gartzke D, Delzer J, Laplanche L, Uchida Y, Hoshi Y, Tachikawa M, Terasaki T, Sydor J, Fricker G
10.1007/s11095-014-1599-5
http://www.ncbi.nlm.nih.gov/pubmed/25522789
18.Quantitative targeted absolute proteomics of rat blood-cerebrospinal fluid barrier transporters: comparison with a human specimen..[J Neurochem,(2015)]Uchida Y, Zhang Z, Tachikawa M and Terasaki T
10.1111/jnc.13147
http://www.ncbi.nlm.nih.gov/pubmed/25951748
19.Contribution of pannexin 1 and connexin 43 hemichannels to extracellular calcium-dependent transport dynamics in human blood-brain barrier endothelial cells..[J Pharmacol Exp Ther,353(1),(2015),192-200]Kaneko Y., Tachikawa M., Akaogi R., Fujimoto K., Ishibashi M., Uchida Y., Couraud P.O., Ohtsuki S., Hosoya K., Terasaki T.
10.1124/jpet.114.220210
http://www.ncbi.nlm.nih.gov/pubmed/25670633
20.Quantitative targeted absolute proteomics for 28 human transporters in plasma membrane of Caco-2 cell monolayer cultured for 2, 3, and 4 weeks..[Drug Metab Pharmacokinet,30(2),(2015),205-208]Uchida Y, Ohtsuki S, Kamiie J, Ohmine K, Iwase R, Terasaki T
10.1016/j.dmpk.2014.11.002
http://www.ncbi.nlm.nih.gov/pubmed/25770030
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