Original Papers- DOI Takayuki -
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[2019]
1.Palladium(0)-Catalyzed [4+2] Annulation of Salicylaldehydes and Propargyl Carbonates to Produce 3,4-Dihydro-2-Methylene-2H-1-Benzopyran-4-Ols.[Chemistry Letters,48(11),(2019),1402-1405]Ayumu Kawase, Hirotaka Omura, Takayuki Doi, and Hirokazu Tsukamoto
10.1246/cl.190642
2.Key Factors for High Diastereo- and Enantioselectivity of Umpolung Cyclizations of Aldehyde-Containing Allylpalladium Intermediates.[Bulletin of the Chemical Society of Japan,92(10),(2019),1743-1753]Hirokazu Tsukamoto, Ayumu Kawase, Hirotaka Omura, and Takayuki Doi
10.1246/bcsj.20190167
3.Structure-Activity Relationship Study on Col-003, a Protein-Protein Interaction Inhibitor between Collagen and Hsp47.[Chemical & Pharmaceutical Bulletin,(2019)]Masahito Yoshida, Masazumi Saito, Shinya Ito, Koji Ogawa, Naoki Goshima, Kazuhiro Nagata,* and Takayuki Doi
10.1248/cpb.c19-00634
4.Synthesis of a Biphenylalanine Analogue of Apratoxin a Displaying Substantially Enhanced Cytotoxicity.[Heterocycles,101,(2019)]Yuichi Onda, Kazuki Fukushi, Kosuke Ohsawa, Masahito Yoshida, Yuichi Masuda, and Takayuki Doi
10.3987/COM-19-S(F)35
5.Palladium(0)-Lithium Iodide-Cocatalyzed Asymmetric Hydroalkylation of Conjugated Enynes with Pronucleophiles Leading to 1,3-Disubstituted Allenes.[Organic Letters,21(17),(2019),6811-6814]Hirokazu Tsukamoto, Tatsuya Konno, Kazuya Ito, and Takayuki Doi
10.1021/acs.orglett.9b02439
6.Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension..[Circulation research,125(3),(2019),309-327]Ryo Kurosawa, Kimio Satoh, Nobuhiro Kikuchi, Haruhisa Kikuchi, Daisuke Saigusa, Md Elias Al-Mamun, Mohammad A H Siddique, Junichi Omura, Taijyu Satoh, Shinichiro Sunamura, Masamichi Nogi, Kazuhiko Numano, Satoshi Miyata, Akira Uruno, Kuniyuki Kano, Yotaro Matsumoto, Takayuki Doi, Junken Aoki, Yoshiteru Oshima, Masayuki Yamamoto, Hiroaki Shimokawa
10.1161/CIRCRESAHA.119.315229
http://www.ncbi.nlm.nih.gov/pubmed/31195886
7.Total Synthesis and Structural Revision of Cyclotetrapeptide Asperterrestide A.[The Journal of Organic Chemistry,84(11),(2019),6765-6779]Kosuke Ohsawa, Masato Sugai, Linnan, Zhang, Yuichi Masuda, Masahito Yoshida, and Takayuki Doi
10.1021/acs.joc.9b00526
8.First Total Synthesis of Palmarumycin C6 Based on Double Oxa-Michael Addition of 1,8-Dihydroxynaphthalene to 3-Bromo-1-indenone.[Heterocycles,99(1),(2019),549-565]Hirokazu Tsukamoto, Yumi Nomura, and Takayuki Doi,
10.3987/COM-18-S(F)52
9.Parallel Synthesis and Biological Evaluation of Destruxin E Analogs Modified with a Side Chain in the alfa-Hydroxycarboxylic Acid Moiety.[European Journal of Organic Chemistry,2019,(2019),1669-1676]Masahito Yoshida, Kenta Adachi, Hayato Murase, Hiroshi Nakagawa, and Takayuki Doi
10.1002/ejoc.201801826
[2018]
10.Synthesis and biological evaluation of thielocin B1 analogues as protein-protein interaction inhibitors of PAC3 homodimer.[Bioorganic Medicinal Chemistry,26(23-24),(2018),6023-6034]Kosuke Ohsawa, Masahito Yoshida, Miho Izumikawa, Motoki Takagi, Kazuo Shin-ya, Naoki Goshima, Takatsugu Hirokawa, Tohru Natsume, and Takayuki Doi
10.1016/j.bmc.2018.11.001
11.Cyclodepsipeptide Natural Products Apratoxins A and C and Their Analogs.[Journal of Synthetic Organic Chemistry, Japan,76(11),(2018),1170-1175]Takayuki Doi, Yuichi Masuda, and Masahito Yoshida
10.5059/yukigoseikyokaishi.76.1170
12.A novel potent ABCB1 modulator, phenethylisoquinoline alkaloid, reverses multidrug resistance in cancer cell.[Molecular Pharmaceutics,15(9),(2018),4021-4030]Norihiko Sugisawa, Shinobu Ohnuma, Hirofumi Ueda, Megumi Murakami, Kyoko Sugiyama, Kosuke Ohsawa, Kuniyuki Kano, Hidetoshi Tokuyama, Takayuki Doi, Junken Aoki, Masaharu Ishida, Katsuyoshi Kudoh, Takeshi Naitoh, Suresh V. Ambudkar, and Michiaki Unno
10.1021/acs.molpharmaceut.8b00457
13.Total Synthesis of Spiromamakone A and Structure Revision of Spiropreussione A.[The Journal of Organic Chemistry,83(16),(2018),9430-9441]Hirokazu Tsukamoto, Shogo Hanada, Yumi Nomura, and Takayuki Doi
10.1021/acs.joc.8b01075
14.Conjugate Addition to Acylketene Acetals Derived from 1,8-Dihydroxynaphthalene and Its Application To Synthesize the Proposed Structure of Spiropreussione A.[Organic Letters,20(10),(2018),3140-3143]Hirokazu Tsukamoto, Yumi Nomura, Koichi Fujiwara, Shogo Hanada, and Takayuki Doi,
10.1021/acs.orglett.8b01259
15.Synthesis of multiple-substituted dihydrofurans via palladium-catalysed coupling between 2,3-alkadienols and pronucleophiles.[Chemical Communications,54(40),(2018),5102-5105]Hirokazu Tsukamoto, Kazuya Ito, and Takayuki Doi
10.1039/C8CC02589D
16.Total Synthesis and Biological Evaluation of Siladenoserinol A and its Analogues.[Angew Chem Int Ed,57(18),(2018),5147-5140]Masahito Yoshida, Koya Saito, Hikaru Kato, Sachiko Tsukamoto, and Takayuki Doi
10.1002/anie.201801659
[2017]
17.Total synthesis and stereochemistry revision of mannopeptimycin aglycone.[J. Syn. Org. Chem. Jpn,75(12),(2017),1274-1285]Shinichiro Fuse, Hiroshi Tanaka, Takashi Takahashi, Takayuki Doi
18.Systematic Analysis of the Relationship among 3D Structure, Bioactivity, and Membrane Permeability of PF1171F, a Cyclic Hexapeptide with Paralyzing Effects on Silkworms.[JOURNAL OF ORGANIC CHEMISTRY,82(21),(2017),11447-11463]Yuichi Masuda, Ren Tanaka, A. Ganesan, Takayuki Doi
10.1021/acs.joc.7b01975
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=TohokuUniv&SrcApp=TohokuUniv&DestLinkType=FullRecord&KeyUT=WOS:000414724000014&DestApp=WOS
19.A small compound inhibiting collagen-specific molecular chaperone as a potential remedy for fibrosis.[J. Biol. Chem.,292(49),(2017),20076-20085]Shinya Ito, Koji Ogawa, Koh Takeuchi, Motoki Takagi, Masahito Yoshida, Takatsugu Hirokawa, Shoshiro Hirayama, Kazuo Shin-ya, Ichio Shimada, Takayuki Doi, Naoki Goshima, Tohru Natsume, Kazuhiro Nagata
10.1074/jbc.M117.815936
20.Stereoselective Synthesis of beta-Amino Acid Derivatives by Asymmetric Mannich Reaction in Flow.[BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN,90(10),(2017),1157-1163]Masahito Yoshida, Koji Umeda, Takayuki Doi
10.1246/bcsj.20170194
http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=TohokuUniv&SrcApp=TohokuUniv&DestLinkType=FullRecord&KeyUT=WOS:000411364300006&DestApp=WOS
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