Original Papers- TOKUYAMA Hidetoshi -
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[2020]
1.Total Syntheses of (–)-emestrin H and (–)-asteroxepin.[Tetrahedron,(2020)]Kanato Umeki, Yusuke Ueda, Juri Sakata, Hidetoshi Tokuyama
2.A Concise Enantioselective Total Synthesis of (–)-Deoxoapodine.[Angewandte Chemie International Edition,(2020)]Kei Yoshida, Kosuke Okada, Hirofumi Ueda, Hidetoshi Tokuyama
3.Cyclic Sulfamidite as Simultaneous Protecting Group for Amino Alcohols: Development of a Mild Deprotection Protocol Using Thiophenol.[Chemical and Pharmaceutical Bulletin,68,(2020)]Juri Sakata, Kazunari Akita, Manabu Sato, Masashi Shimomura, Hidetoshi Tokuyama
4.Divergent Total Syntheses of Isobatzellines A/B and Batzelline A.[Organic Letters,22,(2020),6239-6243]Yumi Yamashita, Louna Poignant, Juri Sakata, Hidetoshi Tokuyama
10.1021/acs.orglett.0c01894
5.Nitrile Synthesis by Aerobic Oxidation of Primary Amines and in situ Generated Imines from Aldehydes and Ammonium Salt with Grubbs Catalyst.[Advanced Synthesis & Catalysis,362,(2020),3583-3588]Tatsuki Utsumi, Kenta Noda, Daichi Kawauchi, Hirofumi Ueda, Hidetoshi Tokuyama
10.1002/adsc.202000663
6.Aerobic Dehydrogenation of N‐Heterocycles with Grubbs Catalyst: Its Application to Assisted‐Tandem Catalysis to Construct N‐Containing Fused Heteroarenes.[Chemistry – A European Journal,(2020)]Daichi Kawauchi, Kenta Noda, Yoshiyuki Komatsu, Kei Yoshida, Hirofumi Ueda, Hidetoshi Tokuyama
10.1002/chem.202001961
7.Total Synthesis of (−)-Lepadiformine A via Radical Translocation–Cyclization Reaction.[Organic Letters,22(9),(2020),3313-3317]Masashi Shimomura, Manabu Sato, Hiroki Azuma, Juri Sakata, and Hidetoshi Tokuyama*
10.1021/acs.orglett.0c00474
[2019]
8.Total Synthesis of Alkaloids based on Late-Stage Oxidation.[MEDCHEM NEWS,29(4),(2019),167-172]TOKUYAMA Hidetoshi
9.Identification of Emetine as a Therapeutic Agent for Pulmonary Arterial Hypertension: Novel Effects of an Old Drug..[Arteriosclerosis, thrombosis, and vascular biology,39(11),(2019),2367-2385]Mohammad Abdul Hai Siddique, Kimio Satoh, Ryo Kurosawa, Nobuhiro Kikuchi, Md Elias-Al-Mamun, Junichi Omura, Taijyu Satoh, Masamichi Nogi, Shinichiro Sunamura, Satoshi Miyata, Hirofumi Ueda, Hidetoshi Tokuyama, Hiroaki Shimokawa
10.1161/ATVBAHA.119.313309
http://www.ncbi.nlm.nih.gov/pubmed/31533472
10.Fluorescent Labeling Method Re-Evaluates the Intriguing Thermoresponsive Behavior of Poly(acrylamide-co-acrylonitrile)s with Upper Critical Solution Temperatures.[Macromolecules,52,(2019)]Chie Otsuka, Yuko Wakahara, Kohki Okabe, Juri Sakata, Masaki Okuyama, Akinobu Hayashi, Hidetoshi Tokuyama, Seiichi Uchiyama
10.1021/acs.macromol.9b00880
11.薬学におけるナノゲル研究の最前線.[ファルマシア,55(8),(2019),770-774]内山 聖一, 徳山 英利
10.14894/faruawpsj.55.8_770
12.Synthesis of Propargylic Ethers by Gold-Mediated Reaction of Terminal Alkynes with Acetals.[Chemical and Pharmaceutical Bulletin,67(8),(2019),872-876]Miyu Furuta, Kyoko Sugiyama, Minami Yamaguchi, Hirofumi Ueda, Hidetoshi Tokuyama
10.1248/cpb.c19-00322
13.Total Synthesis of (+)-CC-1065 Utilizing Ring Expansion Reaction of Benzocyclobutenone Oxime Sulfonate.[Organic Letters,21(16),(2019),6185-6189]Taku Imaizumi, Yumi Yamashita, Yuki Nakazawa, Kentaro Okano, Juri Sakata, Hidetoshi Tokuyama
10.1021/acs.orglett.9b01690
14.Synthetic Studies on Plakinidines.[Heterocycles,99,(2019),310-323]T. Satoh, T. Adachi, K. Okano, J. Sakata, H. Tokuyama
10.3987/COM-18-S(F)26
15.Double Functionalization of Styrenes by Cu-mediated Assisted Tandem Catalysis.[European Journal of Organic Chemistry,15,(2019),2056-2060]D. Kawauchi, H. Ueda, H. Tokuyama
10.1002/ejoc.201900088
16.Rapid Assembly of Protoilludane Skeleton through Tandem Catalysis: Total Synthesis of Paesslerin A and Its Structural Revision.[Organic Letters,21,(2019),3954-3958]Y. Mogi, K. Inanaga, H. Tokuyama, M. Ihara, Y. Yamaoka, K. Yamada, K. Takasu
10.1021/acs.orglett.9b01089
17.Construction of Indole Structure on Pyrroloindolines via AgNTf2-Mediated Amination/Cyclization Cascade: Application to Total Synthesis of (+)-Pestalazine B.[Organic Letters,21,(2019),4205-4209]H. Hakamata, H. Ueda, H. Tokuyama
10.1021/acs.orglett.9b01399
[2018]
18.Novel Potent ABCB1 Modulator, Phenethylisoquinoline Alkaloid, Reverses Multidrug Resistance in Cancer Cell..[Molecular pharmaceutics,15(9),(2018),4021-4030]Norihiko Sugisawa, Shinobu Ohnuma, Hirofumi Ueda, Megumi Murakami, Kyoko Sugiyama, Kosuke Ohsawa, Kuniyuki Kano, Hidetoshi Tokuyama, Takayuki Doi, Junken Aoki, Masaharu Ishida, Katsuyoshi Kudoh, Takeshi Naitoh, Suresh V Ambudkar, Michiaki Unno
10.1021/acs.molpharmaceut.8b00457
http://www.ncbi.nlm.nih.gov/pubmed/30052463
19.A Cell-Targeted Non-Cytotoxic Fluorescent Nanogel Thermometer Created with an Imidazolium-Containing Cationic Radical Initiator.[Angewandte Chemie - International Edition,57(19),(2018),5413-5417]Seiichi Uchiyama, Toshikazu Tsuji, Kyoko Kawamoto, Kentaro Okano, Eiko Fukatsu, Takahiro Noro, Kumiko Ikado, Sayuri Yamada, Yuka Shibata, Teruyuki Hayashi, Noriko Inada, Masaru Kato, Hideki Koizumi, Hidetoshi Tokuyama
10.1002/anie.201801495
http://www.scopus.com/inward/record.url?eid=85044871810&partnerID=40
20.Synthesis of 9,10-Diarylanthracenes via Mg(TMP)2·2LiCl-Mediated Benzyne Generation/[4+2] Cycloaddition and Deoxygenation of 9,10-Epoxyanthracene Intermediates.[Synlett,(2018),513-518]N. Miyamoto, Y. Nakazawa, T. Nakamura, K. Okano, S. Sato, Z. Sun, H. Isobe, H. Tokuyama
10.1055/s-0036-1591510
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