Researchers Information
Photo



Research Activities

Books, Original Papers & Review Papers
Name
OGAWA Tomohisa
Affiliation
Graduate School of Life Sciences
Department of Molecular and Chemical Life Sciences
Division of Chemical Biology
Laboratory of Applied Biological Molecular Science
Title
Associate Professor
Research Fields
  • Applied Biochemistry(Protein engineering)
  • Molecular biology(Molecular evolution)
  • Structural biochemistry(Biochemistry)
display all
Research Subjects
  • Molecular diversification of protein structures and functions via accelerated evolution(1989-)
  • Molecular Mechanism of Bio-mineralization and Its Development to The Novel Nano-Technology(2004-)
  • Study on the stucture and function relationship of lectins(1996-)
display all
Keywords
protein, protein engineering, molecular evolution, genome, lectin, biominerarization, snake venom
Academic Society Membership
  • 日本生化学会
  • 日本農芸化学会
  • 日本化学会
display all
Activity of Academic Society (Post)
    display all
    Books

    Protein Engineering -Technology and Application: Experimental molecular archeology: reconstruction of ancestral mutants and evolutionary history of proteins as a new approach in protein engineering..[InTech,(2013)]Tomohisa Ogawa and Tsuyoshi Shirai
    ISBN980-953-307-520-9


    Lectin Methods and Protocols Part4, Method in Molecular Biology: Tracing Ancestral Specificity of Lectins: Ancestral Sequence Reconstruction Method as a New Approach in Protein Engineering.[Humana Press,(2014)]Tomohisa Ogawa and Tsuyoshi Shirai
    ISBN1064-3745


    生物化学実験法 52 レクチン研究法.[Japan Scientific Societies Press,(2007)]小川智久,村本光二


    display all
    Original Papers

    Novel Matrix Proteins of Pteria penguin Pearl Oyster Shell Nacre Homologous to the Jacalin-Related β-Prism Fold Lectins.[PLoS ONE,9(11),(2014),e112326-]Naganuma T, Hoshino W, Shikanai Y, Sato R, Liu K, Sato S, Muramoto K, Osada M, Yoshimi K, Ogawa T.
    10.1371/journal.pone.0112326


    Tracing Protein Evolution through Ancestral Structures of Fish Galectin..[Structure,19(5),(2011),711-721]Ayumu Konno, Atsushi Kitagawa, Mizuki Watanabe, Tomohisa Ogawa, Tsuyoshi Shirai
    10.1016/j.str.2011.02.014


    Allosteric regulation of the carbohydrate-binding ability of a novel conger Eel galectin by D-mannoside.[Journal of Biological Chemistry,287,(2012),31061-31072]Mizuki Watanabe, Osamu Nakamura, Koji Muramoto and Tomohisa Ogawa
    10.1074/jbc.M112.346213


    Reconstruction of a Probable Ancestral Form of Conger Eel Galectins Revealed.[Molecular Biology and Evolution,24(11),(2007),2504-2514]Ayumu Konno, Tomohisa Ogawa, Tsuyoshi Shirai, Koji Muramoto


    Accelerated evolution of Trimeresurus flavoviridis venom gland phospholipase A2 isozymes.[Proceedings of the National Academy of Science of the United State of America,90(13),(1993),5964-5968]NAKASHIMA K, OGAWA T, ODA N, HATTORI M, SAKAKI Y, KIHARA H, OHNO M


    display all
    Review Papers

    Molecular Evolution of Snake Toxins : Is the Functional Diversity of Snake Toxins Associated with a Mechanism of Accelerated Evolution?.[ACADEMIC PRESS INC, 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 USA PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY,59, (1998), 307-364]Ohno M, Menez R, Ogawa T, Danse JM, Shimohigashi Y, Fromen C, Ducancel F, Zinn-Justin S, Le Du MH, Boulain JC, Tamiya T, Menez A


    Changes of protein structure and function on accelerated evolution: A case of fish galectin.[Kyoritu publications Co. Protein, Nucleic acid and Enzyme,48(14), (2003), 1913-1919]Tsuyoshi Shirai, Clara Shionyu-Mitsuyama, Tomohisa Ogawa


    Molecular diversity and accelerated evolution of C-type lectin-like proteins from snake venom.[Toxicon,45(1), (2005), 1-14]Ogawa T, Chijiwa T, Oda-Ueda N, Ohno M


    Molecular diversity of proteins in biological offense and defense systems..[Molecular Diversity,10(4), (2006), 511-514]Ogawa Tomohisa


    display all
    Honours, Awards and Prizes
      display all
      Updated on
      2017.05.08
      JapaneseTop
      copyright(c)2005 Tohoku University